How does rheumatic fever cause aortic regurgitation?

Rheumatic fever is a complication of strep throat and was once a common childhood illness in the United States. It can cause the aortic valve to become stiff and narrow (stenosis), causing blood to leak.

How does rheumatic fever affect the heart?

Rheumatic fever can cause permanent damage to the heart, including damaged heart valves and heart failure. Treatments can reduce damage from inflammation, lessen pain and other symptoms, and prevent the recurrence of rheumatic fever.

Can rheumatic fever cause aortic stenosis?

Rheumatic fever can lead to scarring of the tissue in the aortic valve, causing the valve to become constricted and narrowed. This scarring can also increase the likelihood of calcium deposits building up along the valve — a major risk factor for aortic valve stenosis in adulthood.

How does VSD cause aortic regurgitation?

As the velocity of a fluid increases a low-pressure zone is created, this is the Venturi effect and it explains the pathogenesis of aortic valve prolapse (AVP) and aortic insufficiency (AI) that is observed in a subset of patients with a ventricular septal defect (VSD).

How does rheumatic fever cause valve disease?

In some people, repeated strep infections cause the immune system to react against the tissues of the body including inflaming and scarring the heart valves. This is what is referred to as rheumatic fever. Rheumatic heart disease results then from the inflammation and scarring of heart valves caused by rheumatic fever.

Why is mitral valve commonly affected in rheumatic fever?

How does rheumatic fever damage the heart? This infection causes swelling and muscle damage to the heart. It can also damage the heart valves in a way that keeps the blood from moving through the heart normally. The infection can cause heart valve leaflets to stick together, which narrows the valve opening.

How does rheumatic heart disease cause AFIB?

People with RHD are at risk of AF because heart valve damage changes the shape of the heart and increased the risk of AF. AF tends to make heart failure worse, increasing shortness of breath, and may cause palpitations. AF also significantly increases the risk of stroke.

How does strep affect the heart?

When your body senses the strep infection, it sends antibodies to fight it. Sometimes, these antibodies attack the tissues of your joints or heart instead. If the antibodies attack your heart, they can cause your heart valves to swell, which can lead to scarring of the valve “doors” (called leaflets or cusps).

How does rheumatic fever cause mitral stenosis?

Rheumatic fever. A complication of strep throat, rheumatic fever can damage the mitral valve. Rheumatic fever is the most common cause of mitral valve stenosis. It can damage the mitral valve by causing the flaps to thicken or fuse. Signs and symptoms of mitral valve stenosis might not show up for years.

Are scarlet fever and rheumatic fever the same?

Scarlet fever is an illness that is caused by a bacterial infection. Rheumatic fever is an inflammatory condition that can develop if scarlet fever is not identified and treated early.

Does rheumatic fever only affect the mitral valve?

Although rheumatic fever can affect any heart valve, it most commonly affects the mitral valve which lies between the two chambers of the left side of the heart. The damage can cause valve stenosis, valve regurgitation and/or damage to the heart muscle.

Can rheumatic fever cause cardiomyopathy?

Traditionally, emphasis has been placed on the valvular damage in rheumatic heart disease, but there is considerable evidence for myocardial involvement. An abnormal immune response to some as yet unrecognized somatic or extracellular antigen of the group A streptococcus is probably related to the cardiomyopathy.

Can rheumatic fever cause permanent joint damage?

Rheumatic fever doesn’t have a cure, but treatments can manage the condition. Getting a precise diagnosis soon after symptoms show up can prevent the disease from causing permanent damage. Severe complications are rare. When they occur, they may affect the heart, joints, nervous system or skin.

Can rheumatic fever cause joint problems later in life?

Usually, heart and joint ailments are long-term consequences of RF. The following are some of the long-term side effects of RF: Heart valve damage: Rheumatic heart disease (RHD) is one of the most common complications of RF.

What is rheumatic atrial fibrillation?

Atrial fibrillation (AF) is a common complication of rheumatic mitral stenosis (MS) and has an impact on event-free survival, either spontaneously or after intervention on the mitral valve.

What are the complication of rheumatic fever?

The most serious complication of rheumatic fever is rheumatic heart disease (RHD). RHD is the most common cause of heart problems in children worldwide and can lead to damage to the heart valves and chronic heart failure. Rheumatic fever is preventable by treating strep throat with antibiotics, usually penicillin.

Can heart problems cause low grade Fever?

Heart disease symptoms caused by heart infection Heart infection signs and symptoms can include: Fever. Shortness of breath. Weakness or fatigue.

Is rheumatic heart disease autoimmune?

Rheumatic fever (RF) and its major sequelae rheumatic heart disease (RHD) are autoimmune diseases that arise following infection of the throat by S. pyogenes in children and young individuals (3–19 years old) who present genetic components that confer susceptibility to the disease.

Does rheumatic fever cause aortic aneurysm?

Rheumatic fever usually does not cause an ascending aortic aneurysm. Depending on the etiology, surgery is needed when the aneurysm reaches 5.5 to 6 cm in diameter.

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